Bruker Avance 500 Manual |Free Full PDF

Bruker Avance 500 Manual |Free Full PDF

ENTER SITE »»» DOWNLOAD PDF
CLICK HERE »»» BOOK READER

File Name:Bruker Avance 500 Manual |Free Full PDF.pdf
Size: 3932 KB
Type: PDF, ePub, eBook

Category: Book
Uploaded: 7 May 2019, 18:38 PM
Rating: 4.6/5 from 606 votes.

Status: AVAILABLE

Last checked: 15 Minutes ago!

In order to read or download Bruker Avance 500 Manual |Free Full PDF ebook, you need to create a FREE account.

Download Now!

eBook includes PDF, ePub and Kindle version

✔ Register a free 1 month Trial Account.

✔ Download as many books as you like (Personal use)

✔ Cancel the membership at any time if not satisfied.

✔ Join Over 80000 Happy Readers

Bruker Avance 500 Manual |Free Full PDFThe suite includes: TopSpin 4.0.3, ICON-NMR, and NMR-SIM. Each TRX1200 provides a full broad banded transmit and a full broad banded receive channel up to 1.2 GHz. Manual push-button sample exchange. Supports all common sample-tubes in spinners or shuttles. Automatic Tuning and Matching (ATM) capabilities. The suite includes: TopSpin 3.5p17, ICON-NMR, and NMR-SIM. Automatic Tuning and Matching (ATM) capabilities. Automatic Tuning and Matching (ATM) capabilities. We recommend you update your browser: Chrome - Firefox - Internet Explorer - Safari. It is used for VT, reaction monitoring and hetero-nuclear NMR experiments.It is used for extended variable temperature and hetero-nuclear NMR experiments in additon to regular proton and carbon ones.It is fully automated with a SampleXpress autosampler. It is located at B530 of Silverman Hall.In addtion, it has ultrahigh 19F sensitivity, the best around Chicago area.It is dedicated for high-throughput application. All the hetero-nuclear NMR experiments can benefit from the high sensitivity and convinience of the SampleXpress auto sampler.It also has wide variable temperature capability. We have two solid-state probes on this system. The Bruker 4 mm HX probe is for most of route work. The Phoenix 1.6 mm HFX probe can be used for 19F and 1H with spinning rate up to 40K Hz. Small-group training is offered on a continuous basis. In addition, the Facility offers lectures for inclusion in existing classes or seminars geared to departmental series and informal presentations at group meetings. Topics generally focus on local applications of NMR, but can include more general discussions of theory and practice. A full spectroscopic and interpretive service is offered, as well as assistance and training for researchers who wish to perform their own experiments.http://alliedteamworkconstruction.com/nbloom/fckuploads/consew-sewing-machine-repair-manuals.xml

Tags:
• bruker avance 500 manual, bruker avance 500 manual pdf, bruker avance 500 manual download, bruker avance 500 manual 2017, bruker avance 500 manual 2016.

Instrumentation includes: a Bruker Avance II 800 MHz equipped with a TCI cryoprobe and 60 sample changer with barcode reader, a Bruker Avance NEO 600 MHz with a QCI-P cryoprobe, and a Bruker Avance II 500 MHz with a TXI probe and 60 sample changer with barcode reader. PDF Version. To create a login, please visit this Bruker link. The magnet and samplechanger were installed in 2011, and the console and Prodigy probe were installed in July 2013. It is located in 194 Kolthoff Hall. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. This instrument is run in manual mode, but automation is available with a SampleCase autosampler. It is located in 196 Kolthoff Hall. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The University of Minnesota is an equal opportunity educator and employer. Privacy Statement. You can find important information here about hardware and software updates, any known problems that might exist, or recent changes in the instrument configuration that you should be aware about. Topics are listed starting from the most recent posting. If you are looking for information on a specific topic, use the find command on your browser. Thus, if you see this error, its just a bug a can be safely ignored. A fix for this will be issued in version 3.5 of the software which will be released in about a month from now. I have tested this, and indeed it seems to correct the problem. In general, whether one is using the “wobb” command or the “atmm”, my recommendation is that you enter the acquisition window (by typing “acqu”) prior to issuing the command that initiates the wobble procedure (“wobb” or “atmm”) The only unresolved issues at this point include the “edc” bug and the 1H atmm bug (note the edc bug is now occurring on all three spectrometers).https://complektuha.com/UserFiles/consew-sewing-machine-manual.xml This will enable rebuilding the SGI host computer which was inadvertantly damaged while attempting to troubleshoot a software problem.The SGI host computer for the avance500 has been changed from a low capacity UPS to the UPS system that is used to supply electrical power to the NMR consoles. This is a big improvement since the low capacity UPS previously used was only capable of holding the computer for about 10 minutes (which obviously caused problems during extended power outages). The UPS system that supplies NMR consoles (and which now supplies the SGI host computers) is much more reliable in this regard since it a) has a much higher capacity and b) because it is wired into the buildings emergency power system. Thus, in an extended power outage situation, the UPS will initially hold the spectrometers and computers via its large internal batteries. After about 2-3 minutes, the buildings emergency power will become active (comes from a large diesel generator located behind the building), which will then supply the UPS and rechage its batteries. After normal power has been restored, the UPS will handle this switchover as well. NOTE, that this change applies to all three NMR spectrometers, not just the avance500. The problem was due to a bad board which was replaced. Note, in addition to the led display on the bsms keypad, you can also visulize the acb display from the “windows” menu in xwinnnmr. Most generally what happens is that atmm initiates a wobble curve with a 40 MHz sweep width (from 480 to 520 MHz), but only the first 10 MHz of this is displayed (480 to 490 MHz). The problem is that under these circumstances the curve is not accurately displayed (it is labeled as being centered about 500.13 MHz with the scale ranging between 495 MHz and 505 MHz). The solution to this is to click the WOBB-SW button on the left of the screen (after having typed “atmm” and after having entered the acquisition window by typing “acqu”).http://www.familyreunionapp.com/family/events/draytek-3300v-manual Once you have clicked the WOBB-SW button, accept the default values. This should then cause the wobble curve and display to reset and properly display (from 480 to 520 MHz, centered at 500 MHz). Note that even though this is correct, it may still seem “unusual” to you. The reason for this is that in order for the atmm procedure to work correctly the wobble sw must be 40 MHz. This is somewhat larger than the 10 MHz that has been used in the past when we tune the 1H channel manually, so you “see” more of the wobble curve. Additionally, a new sgi o2 computer, a new shim stack, and two new probes were installed. The new probes are: These data files have been copied over to the sgi nis cluster: This opens a preferences box. Once you have done this, go to the file menu and choose save as default (otherwise these settings will be lost).Unless noted otherwise, all experiments setup under “ref” are setup use this convention. You should be able to use these as a starting point for your experiments. Major Differences. Relative to the amx500, there are many differences with regard to the hardware available and how to operate the spectrometer. Relativeto the avance600, the number of differences are relatively small. The most important of these is the tuning. Thus, unlike the current 600 setup, avance500 is equipped with two X-BB preamps. Thus, the current hardware setup has both the 15N and 13C channels routed through preamps. This means that there is no need to change the cabling when tuning the 15N channel on the probe. The other difference is the way in which the tuning is performed when the txi probe is in place (which is currently the case). To tune using this probe, simply read in the tuning expt you wish to perform (tune15n.xxx) and then type atmm (this is instead of wobb; if you have the qxi probe, obviously you type wobb instead of atmm) which initiates the same type of “wobble” procedure as before.https://www.ortorehab.se/images/canon-gl2-manual-download.pdf You can view the wobble curve by going to the acquisition window (acqu). Here you will not only see the familiar tuning curve, but you will also see a graphical panel that allows you to adjust the tuning and matching capacitors for the channel being tuned.Presumably its reasonably close (1-2 degrees at room temperature), but not perfect. If the exact temperature is important, you should probably check this using the ethylene glycol sample and the procedure described on the nmr facility web pages. Its on the lab bench in the 600 room. This is the only printer setup from within topspin. This will bring up a dialog box. For the CURPRIN and CURPLOT entries, you should choose hpclj. For printing spectra you can use the “plot” command; for printing parameters you can use the “lpa” command. See the topspin manual for more details on these commands. Note that the nmr facility laser printer is also accessible from the unix command line.Since most users are not using edasp, this change should not have any major impact for most users. There are two potential ways to fix this. One is to minimize the topspin main window, move the cursor into the sgi window where topspin was stared, hold down simultaneously the ctrl and backslash commands (causes topspin graphics to restart), reopen the topspin main window, and go back into the acqusition windown (i.e. type “acqu”). The other way is to click on the button that says wobb-sw (on the left after having initiated wobb or atmm and after having typed “acqu”). The circumstances that causes this is when edc is used to copy a data set from one user (say “ref”) to another (say “ahinck”). This is bogus as you will see that topspin is in fact able to write the data as requested. This is a caused by a hardware problem. In lieu of this, you can use the graphical acb display (type “acbdisp” at the topspin command line). Health information on this site is not meant to be used to diagnose or treat conditions. Consult a health care provider if you are in need of treatment. Click options at top of grey window. Click Start, a new window appear 12. Click lock to open lock window. A continuous Press Z1 again and continue shimming to maximize The software now will begin to do an automatic determination of the When done with data collection and plotting, click continue routine flow chart window 17. Click eject and terminate, remove sample If you want to collect data on a different sample, click insert. The spectrometer is equipped with a Bruker SmartProbe which provides the highest X-nuclei sensitivity across a broad-band channel that can be tuned from 15N to 19F. Contact us to find out our current rates. Generally we have developed these training manuals ourselves, but they often contain content taken from vendor-produced manuals, and almost always contain screen shots of the instrument software. As part of your training and use of the CIF instrumentation you may print a copy for your personal use. Do not provide the manual to anyone else. These manuals are intended strictly for use in the ISU Chemical Instrumentation Facility. The NMR unit has successfully introduced researchers to such uncommon techniques as heteronuclear (mono and bidimensional) experiments, diffusion experiments and kinetic measurements. This instrument also has a BACS-120 auto sampler for 120 samples.Additionally it has an HR-MAS probe for gel-phase samples and TBO (Triple Broadband Observe) and TXI (1H-31P-103Rh) probes in combination with a third channel. This instrument also has a BACS-60 auto sampler for 60 samples.This instrument also has a BACS-60 auto sampler for 60 samples.You can get more information or change the settings of your browser by clicking here. This instrument is also equipped with gradient accessories, including a triple-axis gradient probe collar for gradient MAS studies and a Z-axis high power (60 A) gradient probe for diffusion studies.editorialbuencamino.com/userfiles_editorial/files/Dodge-2500-Manual-Transmission-For-Sale.pdf The spectrometer is equipped with 4 RF channels and 3 high power RF amplifiers. Typical researchers come from a wide range of disciplines such as chemistry, geology, biochemistry, biology, pharmacy, or engineering. The technique has many useful applications: A Bruker 5mm TXI probe is usually installed. Therefore, it is not preferable for C-13 observing experiments. A Bruker 5mm BBFO probe is usually installed, tunable to most BB-channel nuclei (including F-19). It runs Automation NMR experiments via IconNMR, with a Bruker 5mm BBO probe. A Bruker 5mm BBO probe is usually installed, tunable to most BB-channel nuclei (excluding F-19). Not what one usually does without having at least learned to fly a small plane. We recommend starting on the autosampler instrument and then graduating to one of the other spectrometers. There is much to learn and it is best done in small bits. Please contact Dr. Jianfeng Zhu to arrange a training session. The facility house five NMR spectrometers: Varian VNMRS 500MHz, 400MHz, 300MHz; a Bruker AVANCE Neo 500MHz liquids spectrometers; and a 400MHz Bruker AVANCE III solid-state NMR spectrometer. Please complete the online form to request training. NMR trainings are scheduled on-demand basis when two or more users have requested training. A maximum of 5 trainees will be in a session. After completion of the training NMR UserID will be created. Once you obtain your NetID, contact a member of the facility staff who will add you as a user of the scheduler. Use our web-based NMR scheduling application within our building to sign up for NMR time. You will need a University NetID to gain access to the scheduler. Please read our NMR sign-up rules once you have logged into the NMR scheduling web page. Console: 2 channels. Software: VNMRJ 2.2C Console: 2 channels, Autotune. Probe: AutoXDB with PFG.Console: 3 channels. Probes: 3.2mm MAS CHN (Efree) and 3.2mm MAS HXY All rights reserved. Explore now Read about Title IX. Check dates. Login to VandalStar. With the PRODIGY probe the NMR coil assembly and the preamplifier are cooled by evaporating liquid nitrogen. This achieves extremely efficient operation of the NMR coil and significantly reduces thermal noise resulting in the enhance of the overall signal-to-noise ratio compared to standard room temperature probes. The experiment time is thereby dramatically reduces (about 4 times). Both probes are equipped with a z-gradient assembly.This instrument is operated solely by the NMR Lab manager. The transition from high resolution regime to solid-state takes about 30 min. This instrument is operated by qualified UI users (high resolution NMR) or by the Lab manager (solid-state NMR). The instrument is operated solely by qualified UI users on the first-come basis. Overnight experiments start not earlier than 9 pm and should be pre-reserved. The instrument is used for routine NMR analysis (1D spectra, DEPT, fast-COSY). An additional insert is available to perform experiments with water solutions. The real-time monitoring of radical reaction is available. The liquid He thermostat assembly allows low-temperature (down to 4 K) experiments. These spectrometers are Bruker Avance AVII,AVIII, DMX and DRX series NMR spectrometers and all these are currently running BrukerTOPSPIN software.It has a Bruker US2 shielded magnet and Bruker Avance DRX console with three RF channels suitable for triple resonance experiments. It has a triple axis gradinet amplifier and equipped with 5mm triple resonance (1H, 13C and 15N) probe head with ATMA and Z-gradient coil. This instrument is most suitable for structure determination of biomacrmolecules. It has a Bruker US2 shielded magnet and Bruker Avance DMX console with three RF channels suitable for triple resonance experiments. It has a triple axis gradinet amplifier and equipped with 5mm inverse broadband (BB, 15N-31P) probe head with triple axis gradient coil.This system also has a 5mm BB observe ATMA probewith Z-gradient,and a 10mm BB observe probe. This instrument is most suitable for structure determination of organic and inorganic small and macromolecules It has an Oxford unshielded magnet and Bruker Avance DRX console with three RF channels suitable for triple resonance experiments. It has a triple axis gradinet amplifier and equipped with 5mm QNP (1H, 13C, 19F and 31P) probe head with z-gradient coil. This instrument is most suitable for structure determination of organic and inorganic molecules and polymers. It has an Oxford unshielded magnet and Bruker AV II console with three RF channels suitable for double and triple resonance experiments. It has a z-gradinet amplifier and equipped with 5mm BB observe ATM probe head with z-gradient coil.It runs TOPSPIN 2.1 software on a linux workstation. This instrument is most suitable for structure determination of small organic molecules. It has an Oxford unshielded magnet and BrukerDMX console with Three RF channels suitable for double resonance experiments. This instrument is most suitable for structure determination of small organic molecules. It has a unshielded Oxford magnet and two chanel console.It runs TOPSPIN 2.1 on a linux workstation It has a Bruker shielded magnet with Bruker AVIII console and running TOPSPIN 2.1 sofware on pc workstation. It is a two channel spectrometer with gradient capability. This instrument is primarily used for 11B NMR. It is an open access spectrometer to the users specially permitted to use this instrument. It has a Bruker unshielded magnet with Bruker Avance DMX console and running TOPSPIN on pc workstation. This is an open access spectrometer is used primarily for routine structure determination of small molecules. It has an Oxford unshielded magnet with Bruker Avance DMX console and running TOPSPIN 1.3 on a pc workstation. It is a two channel spectrometer without gradient capability.https://www.edplace.com/userfiles/image/files/Dodge-2500-Manual-Diesel.pdf This is an open access spectrometer is used primarily for routine structure determination of small molecules. It is the ideal machine for ultra high sensitivity 13C and 1H experiments where sample quantity is limited. Diffusion data for small molecules and temperature dependent dynamics in solution can also be studied.Staff may also help out with the evaluation of data. Access for external users to the facilities depend on the present load from internal users. External DCIF users should reach out to us if they have samples that we can help with.Staff are happy to help with instrument training, chemical structure problems and various analytical chemistry questions during the day. Manual-use instruments are reserved using in-house reservation software except during special walk-on times. To get started with an instrument or instruments, please submit the DCIF Training Request Form. Macintosh and Linux computers come with this capability pre-installed; Windows computers typically need to add an SSH program. If you are an external user we can advise you as to applications that are available from third-parties. You will receive your Res1B credentials as part of your instrument training for all non-automation instruments. John has diverse experience in NMR, ranging from small molecule structure determination in drug development to metabolomics to imaging, as well as significant synthetic experience. John holds a Master of Science in Chemistry from Indiana University. Mohan has extensive experience in mass spectrometry, including the analysis of peptides and molecular probes for imaging as well as significant synthetic experience with peptides. Mohan holds a Ph.D. in Bioorganic chemistry from the Indian Institute of Technology and a Master of Science from Bharathidasan University. Bruce has extensive NMR problem solving and novel NMR method development experience, both at Merck and at Varian NMR Systems, where he was an Application chemist for 11 years. Bruce holds a Ph.D. in Chemistry from the University of Wisconsin-Madison in the lab of Professor Barry Trost. It uses ChemStation acquisition and data analysis software and is run in full automation mode using the Agilent Walkup software front-end. In addition to ChemStation data analysis, data files can be analyzed in MassHunter using the LC-SQ Translator. The system operates with an accuracy of 5 ppm and a resolving power of greater than 10,000 (FWHM) in DART positive ion mode.The system also has a syringe pump coupled ESI source that can be used upon request. It is capable of measuring in both linear and reflector mode, and in reflector mode 3-5 ppm mass accuracy can be achieved using an internal calibration standard. The data processing software contains modules for analyzing and sequencing peptides, proteins, and polymers. It typically runs a Jet Stream ESI source, but can also be configured to run in APCI or APPI mode upon request. The system uses MassHunter data acquisition and processing software, with additional Qualitative Navigator, Workflow, Bioconfirm, and Quantitative analysis software packages. The broadband channel extends from 31P down to 15N. Data is returned via standard email, or can be retrieved from an in-lab data server for up to six months. The system runs Bruker Topspin software version 3.5pl7 with IconNMR. The broadband channel extends from 31P down to 15N. Data can be retrieved from an in-lab data server for up to six months. The system runs Bruker Topspin software version 3.5pl7. The broadband channel extends from 19F down to 109Ag. The system runs Bruker Topspin software version 4.0.5 with IconNMR. The broadband channel extends from 31P down to 15N. The system runs Bruker Topspin software version 4.0.5 with IconNMR. The instrument is typically configured for routine solid-state NMR use each Thursday. The system runs Bruker Topspin software version 4.0.5. The broadband channel extends from 31P down to 15N. This system runs in full-automation using a 24 sample carousel, and JEOL Delta software version 5.3. Data can be retrieved from an in-lab data server for up to six months. The SampleJet is capable of handling all of 5mm, 3mm, and 1.7mm samples in automation, and has capacity for 96 standard 7 inch samples plus five 96-well racks of mixed diameter 4 inch tubes. The 96-well racks can be individually heated or cooled on request. The system runs Bruker Topspin software version 4.0.5 with IconNMR. The standard operating temperature range extends from 4.5K at the low end to room temperature or above. The spectrometer runs Xenon 1.1b.155 software. It can measure typical liquid or solid samples directly without the need for additional sample preparation. The spectrometer runs Opus 7.8 software. Filters are also available for the following wavelengths: 577, 546, 435, 365 nm. Users should supply their own polarimetry cells, although we have a couple available for occasional use. This system has a four stream solvent mixing system with binary pump, a diode array detector with the ability to measure from 190 to 640 nm, and a maximum pressure of 600 bar. It also has an autosampler capable of handling both individual vials and well plates. Be careful when blowing up images and pictures beyond 100 as they can become pixelated and blurry. Use large fonts instead of blowing up pictures of text. DCIF Staff prints posters as they are received. We do not proofread, edit, alter or change any of the content, so be sure it is in final form before sending it to us for printing. You should know which account to bill for the poster charge.These can be used to refresh your knowledge of an instrument that you have not used for a while, or to learn something new about an instrument that you have never used. Slides from some of these presentations can be found below. By continuing without changing your cookie settings, you agree to this collection. For more information, please see our University Websites Privacy Notice. The instrumentation serves the high-resolution research needs for investigators from the Departments of Molecular and Cell Biology, Chemistry, and Pharmacy at the University of Connecticut. The Facility is part of the University-wide Partnership for Excellence in Structural Biology and maintains collaborative ties with its sister NMR Facility at the UConn Health Center in Farmington. The services and equipment of the UConn NMR Facility are also available to industry and other academic institutions. The probe has a signal-to-noise ratio 730 for 1H, 550 for 19F, 300 for 13C, 180 for 31P and 40 for 15N. Additionally, any nuclei can be automatically selected and optimally tuned and matched with the auto tune-match (ATM) component. The 500 is an instrument of choice for users with small quantities of a compound or where a higher resolution is necessary, and for multidimensional experiments such as HSQC, HMBC or NOESY. It is used for chemical structure elucidation and supports NMR studies on proteins and nucleic acids.It delivers signal-to-noise ratio 300 for 1H, 275 for 19F, 190 for 13C, 150 for 31P, and 20 for 15N with automatic tuning and matching to selected nuclei. The AVANCE 400 is used for both one-dimensional and advanced two-dimensional experiments.Visit the IMS NMR Laboratory for more information. The NMR Facility Staff provides training and consultation in the use of instruments under their respective supervision. A 24 hour notice is required for scheduling a hands-on training session. This article has been cited by other articles in PMC. Abstract To facilitate the high-throughput acquisition of nuclear magnetic resonance (NMR) experimental data on large sets of samples, we have developed a simple and straightforward automated methodology that capitalizes on recent advances in Bruker BioSpin NMR spectrometer hardware and software. Given the daunting challenge for non-NMR experts to collect quality spectra, our goal was to increase user accessibility, provide customized functionality, and improve the consistency and reliability of resultant data. NMRbot improves automated data acquisition and offers novel tools for use in optimizing experimental parameters on the fly. The investigators reported benefits from ease of setup, improved spectral quality, convenient customizations, and overall time savings. Keywords: NMR spectroscopy, Metabolomics, Compound screening, Automation, Data collection, Python scripting Introduction An increasing number of scientific investigations involve the analysis of large sample sets, often assembled in a range of divergent compositions. One of the best methods for atomic-level characterization of molecules and mixtures is solution-state nuclear magnetic resonance (NMR) spectroscopy (Maher et al. 2008; Shortridge et al. 2008; Xie et al. 2009 ). The unparalleled capabilities of NMR to acquire useful data, however, require a non-trivial level of expertise with an NMR spectrometer and familiarity with its underlying principles. To set up even the simplest one-dimensional experiments requires the spectrometer user to spend several minutes optimizing several hardware and software parameters. For example, the spectrometer probe must be “tuned and matched” for each new sample placed in the spectrometer to maximize the efficiency of radio-frequency (RF) signals sent and received from that sample. In addition, the magnetic field passing through the sample needs to be made as homogeneous as possible in order to optimize spectral lineshapes. This process, called shimming, is achieved by adjusting the electrical current in a multitude of “shim” coils directly adjacent to the sample. Other parameters, such as the range of frequencies to sample (spectral-width, or SW), are difficult to determine a priori, and must be manually deduced for subsequent data collections. Hence, experiment setups for a large set of samples can potentially consume a significant portion of an investigator’s time and effort. In recent years Bruker BioSpin has introduced several hardware and software products that soften the requirements for user technical expertise and promote high-throughput NMR spectroscopy. All these features are especially useful for spectrometers that can be remotely operated. TopSpin includes a legacy software suite, ICON-NMR, for high-throughput data acquisition that incorporates many of the software features described previously. The specific limitations in ICON-NMR include: a restrictive interface with access separate from TopSpin; a complicated and inflexible menu system for sample information entry; reduced performance of automated sample shimming; difficulty in accommodating different solvents in the same sample set; and an inability to adapt experiment parameters to each sample. These limitations provided the impetus to develop a more straightforward, intuitive, high-throughput methodology for automated data acquisition across diverse sample sets. Our goals were to simplify the setup procedure for data acquisition, provide easily customizable functionality, and improve the quality of data acquired over what was previously obtained from ICON-NMR. Methods Automated, high-throughput NMR data collection for large sample sets first requires access to a spectrometer equipped with the automated hardware and software features described in the introduction. For our purposes, we developed and tested this new methodology on four Bruker BioSpin NMR spectrometers at NMRFAM; a 500 MHz Avance III with 5 mm triple resonance cryoprobe, a 600 MHz Avance III with 5 mm quadruple resonance cryoprobe, a 600 MHz Avance III with 1.7 mm triple resonance cryoprobe, and a 700 MHz Avance III with 5 mm quadruple resonance cryoprobe. Each spectrometer was equipped with SampleJet and ATM accessories, running TopSpin v. 3.0 under CentOS 5.